Neuralli® MP

Neuralli® MP comes in capsules packaged in a twist-off bottle. These state-of-the-art CSP vials keep theinside of the bottle very dry and help maintain maximum probiotic potency.

If swallowing the capsule is uncomfortable, you can open the shell and take the powder. (Take it all at once to guarantee its potency.) If you’d like, you can mix Neuralli® MP powder into a cool drink or food of your choice. It should not be added to warm/hot foods or liquids. Read more on the Ways to Take Neuralli MP page.

The FDA approves drugs (or medicines), Neuralli®MP is not a drug or medicine. It is a probiotic medicalfood.
A medical food is defined by 21 U.S. Code 360ee,(b),(3) as a food formulated for consumption orenteral administration under the supervision of a physician for the specific dietary management of adisease or condition for which distinctive nutritional requirements, based on recognized scientifcprinciples, are established by medical evaluation.
Neuralli MP is a medical food intended for the dietary management of autism and Parkinson's disease.Lactiplantibacillus (formerly Lactobacillus) plantarum PS128™ is the probiotic strain that, at suffcientlyhigh quantities, when administered to people with the specified neurological conditions, hasdemonstrated some benefts that are clinically meaningful.
L. plantarum PS128TM is self-affrmed as generally recognized as safe (GRAS). The strain L. plantarumPS128™ is derived from a fermented food. The fermented food itself is not in a typical diet and doesnot have the standardized quantities of the specifc strain, PS128™.To maintain the strain's genetic integrity,it must be cultivated in controlled manufacturing conditions.To deliver a suffcient quantity to have a clinically meaningful effect,Neuralli MP delivers PS128™ in ahigh-potency form.

Take two capsules every day. Many customers take both at the same time; however, you can also split them up if you prefer. Find the time of day that works best for you.

In a clinical study with people with Parkinson’s disease, participants took two capsules in the evening. In other clinical studies the timing was left up to the participants.

The serving size of Neuralli® MP is 2 capsules per day, providing 60 billion CFU of PS128TM. Children as young as 3 years of age have used 60 billion CFUs per day of PS128TM in clinical studies.

Since each person is different, your tolerance may vary. Please take Neuralli® MP under the supervision of your health care provider.

As a medical food, NeuralliMP should be used under the supervision of your health care provider, Itsactive ingredient, PS128™, has been studied in Autistic people and people with Parkinson's (seereferences here).PS128™ may play a role in modulating neurotransmitters such as dopamine and serotonin in someindividuals. If you have concerns about this, please speak with your health care provider before starting
or stopping Neuralli MP.While each ingredient in NeuralliMP has been self-affirmed as Generally Recognized as Safe (GRAS),NeuralliMP has not been tested for safety and effectiveness in populations with other medicalconditions. We recommend that you consult with your health care provider to decide if Neuralli MP isright for you.

Yes, the 60 billion CFU quantity of PS128
™ in Neuralli® MP has been the focus of multiple research and clinical studies.

Preclinical studies suggest that the strain Lactiplantibacillus (formerly Lactobacillus) plantarum PS128TM benefits the immune and digestive systems, as well as impacts mental health by reducing stress, reducing anxiety, and balancing dopamine and serotonin in the brain.

Clinical studies of PS128™ in three randomized, placebo-controlled trials and one real-world study in autism demonstrate clinically meaningful outcomes suggesting a reduction in anxiety. A single arm study in Parkinson's suggested positive benefits of using L. plantarum PS128™  as dietary management.

While many strains of L. plantarum are commercially available as probiotics, the L. plantarum PS128™ strain affected dopamine and serotonin in some parts of the brain in preclinical studies. PS128™ also demonstrated benefits in clinical trials of people with neurological conditions.

In general, different strains of a single bacterial species can have very different beneficial effects. For example, L. plantarum Lpla33 demonstrated benefit in IBS-D. On the other hand, Lactobacillus plantarum LPLDL can help with cholesterol levels. (PS128™ has not been studied for those effects, and neither of those strains have been studied in the way that PS128™ has.)